Systems Glycobiology: Integrating Glycogenomics, Glycoproteomics, Glycomics, and Other ‘Omics Data Sets to Characterize Cellular Glycosylation Processes
详细信息    查看全文
文摘

Glycogenomics, glycomics, and glycoinformatics will help in accelerating the understanding of the role that glycans play in protein therapeutics and diseases.

Recent advancements in glycogenomics, glycomics, glycoproteomics, and glycoinformatics tools to support analysis of glycan experimental measurements and the unique challenges due to interrogation and assimilation of disparate high-throughput glycosylation data sets are summarized in this report.

The era of advanced glycomics can enable discovery of novel glycoproteins and/or glycan biomarkers for diseases and also establish an understanding of the glycosylation behavior of therapeutics based on the glycogenome of the Chinese hamster ovary production host.

Novel methodologies can facilitate the integration of glycan measurements together with other ‘omics data sets that can lead to a better understanding of glycosylation as a complex cellular process.

© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号

地址:北京市海淀区学院路29号 邮编:100083

电话:办公室:(+86 10)66554848;文献借阅、咨询服务、科技查新:66554700