The impact of infarct type on the reliability of early oral glucose tolerance testing in patients with myocardial infarction

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• 作者：Camilla Hage ; Klas Malmberg ; Lars Rydé ; n ; Mä ; rit Wall ; er
• 关键词：Diabetes mellitus ; Myocardial infarction ; Oral glucose tolerance test ; Diagnostic accuracy
• 刊名：International Journal of Cardiology
• 出版年：2010
• 出版时间：19 November 2010
• 年：2010
• 卷：145
• 期：2
• 页码：259-260
• 全文大小：142 K

文摘

Background

Previously unknown glucose perturbations are common in patients with myocardial infarction (MI). We evaluated the accuracy of an early oral glucose tolerance test OGTT in relation to the extent of the MI.

Material and methods

An OGTT was performed in 134 patients with MI without known diabetes (DM) after 4–5 days (predischarge) and 3 months. The MI was classified as transmural (TMI; n = 70) or subendocardial (SEMI; n = 102).

Results

Predischarge TMI-patients had normal GT, impaired GT or DM in 31 % , 33 % and 36 % . These proportions were 35 % , 39 % and 26 % after 3 months. The corresponding proportions in SEMI-patients were 35 % , 35 % and 30 % and 35 % , 40 % and 25 % . At admission and the first 2 days fasting glucose was higher in TMI than SEMI-patients.

Conclusion

The outcome of an early OGTT is valid but the test should not be performed earlier than 4–5 days after the event especially in patients with extensive infarctions.