Expanding clinical laboratory tobacco product evaluation methods to loose-leaf tobacco vaporizers

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• 作者：Alexa A. Lopez ; Marzena Hiler ; Sarah Maloney ; Thomas Eissenberg ; Alison B. Breland ; ^{abbrelan@vcu.edu}
• 关键词：Loose-leaf tobacco vaporizer ; Heat-not-burn products ; Electronic cigarette ; Plasma nicotine ; Carbon monoxide
• 刊名：Drug and Alcohol Dependence
• 出版年：2016
• 出版时间：1 December 2016
• 年：2016
• 卷：169
• 期：Complete
• 页码：33-40
• 全文大小：743 K
• 卷排序：169

文摘

This is the first human laboratory study of a loose-leaf tobacco vaporizer (LLTV). LLTV use significantly increased plasma nicotine concentration, but not CO. LLTV use reduced tobacco abstinence symptom severity, but less so than a cigarette. Both the LLTV and an ECIG were significantly less satisfying than cigarettes. Laboratory methods can be expanded to “heat-not-burn” products.