An expedient one-pot synthesis of highly substituted imidazoles using supported ionic liquid-like phase (SILLP) as a green and efficient catalyst and evaluation of their anti-microbial activity

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• 作者：Maryam Saffari Jourshari ; Manouchehr Mamaghani ; Farhad Shirini ; Khalil Tabatabaeian ; Mehdi Rassa ; Hadiss Langari
• 关键词：SILLP ; Imidazole ; Phenanthroimidazole ; Ionic liquid ; Three-component reaction ; Anti-microbial activities
• 刊名：Chinese Chemical Letters
• 出版年：2013
• 出版时间：November, 2013
• 年：2013
• 卷：24
• 期：11
• 页码：993-996
• 全文大小：354 K

文摘

An efficient method for the synthesis of imidazole derivatives by a three-component condensation of benzil or 9,10-phenanthrenequinone, aldehydes and ammonium acetate using supported ionic liquid-like phase (SILLP) catalyst under ultrasonic irradiation or classical heating conditions is reported. The present methodology offers several advantages, such as excellent yields, simple procedures, short reaction times, simple work-up and mild conditions. The catalyst is easily separated from the products by filtration and also exhibits remarkable reusable activity. These highly substituted imidazoles were also evaluated for their anti-microbial activity.