Should we routinely analyze reduction mammaplasty specimens?

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• 作者：Pä ; ivi A. Merkkola-von Schantz^a ; ^{paivi.merkkola-vonschantz@hus.fi} ; Tiina A. Jahkola^a ; Leena A. Krogerus^b ; Katja S. Hukkinen^c ; Susanna MC. Kauhanen^a
• 关键词：Reduction mammaplasty ; Cancer ; Benign breast disease ; High-risk lesion ; Breast Imaging
• 刊名：Journal of Plastic, Reconstructive & Aesthetic Surgery
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：70
• 期：2
• 页码：196-202
• 全文大小：328 K
• 卷排序：70

文摘

Reduction mammaplasty is one of the most common plastic surgery procedures. Preoperative imaging and histopathology protocols vary among countries and institutions.We aimed to analyze the incidence of occult breast cancer and high-risk lesions in reduction mammaplasty specimens. We also analyzed whether patients with abnormal histopathology differed from the study population in terms of demographics.Patients and methodsIn total, 918 women who underwent reduction mammaplasty from January 2007 to December 2011 were retrospectively reviewed for demographics, preoperative imaging, further preoperative examinations, pathology reports, and postoperative follow-up.ResultsAbnormal histopathological findings were revealed in 88 (10%) patients with a mean age of 49.5 ± 10.2 years. The incidence of breast cancer was 1.2%, and the incidence of high-risk lesions (atypical ductal and lobular hyperplasia and lobular carcinoma in situ) was 5.5%. Age and specimen weights were significantly higher in patients with abnormal histopathology. Eighty-one percent of patients with abnormal histopathology had normal preoperative imaging revealing two high-risk and two cancer findings. Two patients developed breast cancer in the same breast in which the high-risk lesion was originally detected.ConclusionWomen with abnormal histopathology cannot be sufficiently detected preoperatively. Therefore, histopathological analysis of reduction mammaplasty specimens seems mandatory. Reduction mammaplasty combined with subsequent histopathological examination offers a sufficient chance of detecting cancer and risk-increasing lesions that merits the cost of histopathology.