刊名:Biochemical and Biophysical Research Communications
出版年:2017
出版时间:29 January 2017
年:2017
卷:483
期:1
页码:566-571
全文大小:876 K
卷排序:483
文摘
Succinyl-CoA synthetase alpha (SCSα) deficiency was generated in Drosophila. SCS deficient flies contain a high level of succinyl-CoA. SCS deficiency alters the levels of metabolites in TCA cycle and glycolysis. SCS deficiency causes developmental delays and glycogen breakdown. SCS deficiency impairs locomotor activity and reduces survival under starvation.