Brain effects of manganese exposure in mice pups during prenatal and breastfeeding periods
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- 作者：Monica Akemi Okadaa ; maokada86@yahoo.com.br" class="auth_mail" title="E-mail the corresponding author ; Francisco Filipak Netoa ; filipak@ufpr.br" class="auth_mail" title="E-mail the corresponding author ; Cassio Hideo Nosoa ; carmenluvoigh@yahoo.com.br" class="auth_mail" title="E-mail the corresponding author ; Carmen Lú ; cia Voigtb ; cassiohideo@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Sandro Xavier Camposb ; campos@uepg.br" class="auth_mail" title="E-mail the corresponding author ; Ciro Alberto de Oliveira Ribeiroa ; ciro@ufpr.br" class="auth_mail" title="E-mail the corresponding author ; ciro.ribeiro@pq.cnpq.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Manganese ; Mouse ; Brain effects ; Pups ; Parental exposure
- 刊名：Neurochemistry International
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：97
- 期：Complete
- 页码：109-116
- 全文大小：1370 K
文摘
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GST and AChE activity are affected by low doses of Mn in adults and young mice.
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High dose of Mn affects lipids and proteins in mice brain in a dose dependent way.
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Realistic doses of Mn cause effects in brain but not inliver.
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Pups' brain are affected by Mn when the parental females are previously exposed.
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The Mn effects in brain can be associated with manganism or neurodegenerative disturbs.