A critical appraisal of the mild axonal peripheral neuropathy of late neurologic Lyme disease

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• 作者：Gary P. Wormser^a ; ^{gwormser@nymc.edu} ; Franc Strle^b ; Eugene D. Shapiro^c ; Raymond J. Dattwyler^d ; Paul G. Auwaerter^e
• 关键词：Lyme disease ; Borrelia burgdorferi ; Neuropathy ; Peripheral neuropathy ; Neuroborreliosis
• 刊名：Diagnostic Microbiology and Infectious Disease
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：87
• 期：2
• 页码：163-167
• 全文大小：259 K
• 卷排序：87

文摘

In older studies, a chronic distal symmetric sensory neuropathy was reported as a relatively common manifestation of late Lyme disease in the United States. However, the original papers describing this entity had notable inconsistencies and certain inexplicable findings, such as reports that this condition developed in patients despite prior antibiotic treatment known to be highly effective for other manifestations of Lyme disease. More recent literature suggests that this entity is seen rarely, if at all. A chronic distal symmetric sensory neuropathy as a manifestation of late Lyme disease in North America should be regarded as controversial and in need of rigorous validation studies before acceptance as a documented clinical entity.