Bicarbonate and mannitol treatment for traumatic rhabdomyolysis revisited

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• 作者：Jamison S. Nielsen ; D.O. ; M.B.A. ; F.A.C.S.^a ; Mitchell Sally ; M.D. ; F.A.C.S.^a ; ^b ; Richard J. Mullins ; M.D. ; F.A.C.S.^a ; Matthew Slater ; M.D. ; F.A.C.S.^a ; Tahnee Groat ; B.A. ; M.P.H.^b ; Xiang Gao ; B.S.^a ; J. Salvador de la Cruz ; M.D.^a ; Margaret K.M. Ellis ; M.D.^a ; Martin Schreiber ; M.D. ; F.A.C.S.^a ; Darren J. Malinoski ; M.D. ; F.A.C.S.^a ; ^b ; ^{darren.malinoski@va.gov}
• 关键词：Rhabdomyolysis ; Mannitol ; Creatine kinase ; Alkaline diuresis ; Acute kidney injury
• 刊名：The American Journal of Surgery
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：213
• 期：1
• 页码：73-79
• 全文大小：1419 K
• 卷排序：213

文摘

The 2 major treatments for rhabdomyolysis are alkaline diuresis and crystalloid. The use of a rhabdomyolysis protocol with mannitol and bicarbonate remains debated. Use of a rhabdomyolysis protocol was supported for creatinine kinase greater than 10,000 U/L. Evaluation of rhabdomyolysis strategies in a prospective randomized trial is needed.