Acute stress impairs frontocingulate activation during error monitoring in remitted depression

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• 作者：Alexis E. Whitton^a ; ^b ; Ashlee Van&rsquo ; t Veer^a ; ^b ; Pragya Kakani^a ; Daniel G. Dillon^a ; ^b ; Manon L. Ironside^a ; Anja Haile^a ; David J. Crowley^a ; Diego A. Pizzagalli^a ; ^b ; ^{dap@mclean.harvard.edu}
• 关键词：Major depression ; Stress ; Remission ; ERP ; Error-related negativity ; Anterior cingulate
• 刊名：Psychoneuroendocrinology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：75
• 期：Complete
• 页码：164-172
• 全文大小：1049 K
• 卷排序：75

文摘

Stress is a trigger of depression relapse and impairs performance monitoring. In rMDD, stress impaired frontocingulate activation in an error monitoring task. Greater frontocingulate impairment predicted increased depression at 18 months. Results highlight a mechanism by which stress may trigger future depression.