Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells
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- 作者：Marco De Simone1 ; 13 ; Alberto Arrigoni1 ; 13 ; Grazisa Rossetti1 ; 13 ; Paola Gruarin1 ; 13 ; Valeria Ranzani1 ; Claudia Politano1 ; Raoul J.P. Bonnal1 ; Elena Provasi1 ; Maria Lucia Sarnicola1 ; Ilaria Panzeri1 ; Monica Moro1 ; Mariacristina Crosti1 ; Saveria Mazzara1 ; Valentina Vaira1 ; 2 ; 4 ; Silvano Bosari2 ; 4 ; Alessandro Palleschi3 ; Luigi Santambrogio3 ; 4 ; Giorgio Bovo5 ; Nicola Zucchini5 ; Mauro Totis6 ; Luca Gianotti6 ; 7 ; Giancarlo Cesana7 ; Roberto A. Perego7 ; Nirvana Maroni8 ; Andrea Pisani Ceretti8 ; Enrico Opocher8 ; 9 ; Raffaele De Francesco1 ; Jens Geginat1 ; Hendrik G. Stunnenberg10 ; Sergio Abrignani1 ; 11 ; abrignani@ingm.org" class="auth_mail" title="E-mail the corresponding author ; Massimiliano Pagani1 ; 12 ; 14 ; pagani@ingm.org" class="auth_mail" title="E-mail the corresponding author
- 刊名：Immunity
- 出版年：2016
- 出版时间：15 November 2016
- 年：2016
- 卷：45
- 期：5
- 页码：1135-1147
- 全文大小：2946 K
文摘
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Transcriptome analysis performed on tumor-resident CD4+ Th1, Th17, and Treg cells
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Tumor-infiltrating Treg cells are defined by the expression of signature genes
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Treg-specific signature genes correlate with patients’ survival in both CRC and NSCLC