A follow-up study in asymptomatic HIV patients

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• 作者：Fornara ; Carla ; Medaglini ; Stefania ; Cursi ; Marco ; Leocani ; Letizia ; Locatelli ; Tiziana ; Castagna ; Antonella ; et. al.
• 刊名：Electroencephalography and Clinical Neurophysiology
• 出版年：1997
• 出版时间：July, 1997
• 年：1997
• 卷：103
• 期：1
• 页码：81
• 全文大小：133 K

文摘

Many studies analyzed the possible modifications of EEG parameters in asymptomatic HIV patients. In our previous study we considered 37 asymptomatic HIV+ subjects with normal cerebral MRI and cerebrospinal fluid. All patients were submitted to quantified EEG (qEEG). Between all analyzed neurophysiological parameters, only the centroid was altered. This result demonstrated a high sensitivity of the centroid, evident already in early phases of disease. The centroid modification was significantly related to the supposed illness duration. In order to demonstrate the predictive role of this parameter we followed the 50 patients (the first 37 patients and 13 new asymptomatic subjects) in their clinical history examining each therapy modifications and ematochemical alterations. We submitted our subjects to qEEG and analyzed the absolute and relative power and centroids of this frequency bands: delta (0.4-3.9 Hz), theta (4-7.9 Hz), alpha (8-11.9 Hz), beta1 (12-17.9 Hz), beta2 (18-30 Hz). We will discuss the results of the follow-up.