Nonepileptic seizures under levetiracetam therapy

详细信息    查看全文

• 作者：Andrei Ignatenco ; Shahar Arzy ; Joseph Ghika ; Didier Genoud ; Peter W. Kaplan ; Stanislav Groppa ; Margitta Seeck
• 关键词：Levetiracetam ; Nonepileptic seizures ; Psychogenic seizures ; Side effects ; Anxiety ; Depression ; Tumor
• 刊名：Epilepsy & Behavior
• 出版年：2010
• 出版时间：November 2010
• 年：2010
• 卷：19
• 期：3
• 页码：526-527
• 全文大小：122 K

文摘

We describe two patients with epilepsy who presented with nonepileptic seizures (NES) when started on levetiracetam (LEV), which disappeared or significantly decreased when LEV was discontinued. NES are traditionally attributed to psychic trauma often after physical or sexual abuse, whereas the psychiatric side effects of levetiracetam largely encompass depression, hallucinations, and psychosis. We conclude that NES are a rare side effect of LEV treatment and part of the spectrum of behavioral changes observed with LEV treatment.