文摘
A treosulfan-based reduced-toxicity regimen, FluTreo, achieved favorable outcomes in medically infirm acute myeloid leukemia and/or myelodysplastic syndrome patients Outcomes were compared to a historical group that received a reduced intensity busulfan-based conditioning (FluBuATG) The FluTreo group achieved higher survival rates with low relapse mortality, similar toxicity and transplantation-related mortality FluTreo conditioning was the only independent factor associated with favorable survival rates