Healthy live birth using theophylline in a case of retrograde ejaculation and absolute asthenozoospermia

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• 作者：Thomas Ebner ; Omar Shebl ; Richard Bernhard Mayer ; Marianne Moser ; Walter Costamoling ; Peter Oppelt
• 关键词：Absolute asthenozoospermia ; live birth ; motility ; retrograde ejaculation ; theophylline
• 刊名：Fertility and Sterility
• 出版年：February, 2014
• 年：2014
• 卷：101
• 期：2
• 页码：340-343
• 全文大小：140 K

文摘

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Objective

To analyze whether the use of ready-to-use theophylline is a feasible option in a case of retrograde ejaculation and absolute asthenozoospermia.

Design

Case report.

Setting

In聽vitro fertilization unit of a public hospital.

Patient(s)

Thirty-one-year-old nulliparous woman, and 39-year-old male with retrograde ejaculation and absolute asthenozoospermia.

Intervention(s)

Retrieval of postejaculatory urine, restoration of motility using a methylxanthine, intracytoplasmic sperm injection, single-embryo transfer.

Main Outcome Measure(s)

Sperm motility, fertilization, embryo quality, live birth.

Result(s)

Successful fertilization and a single-embryo transfer resulted in a healthy live birth.

Conclusion(s)

Theophylline turned out to be a safe, efficient agent for stimulating immotile spermatozoa in patients with retrograde ejaculation.