Acute and prolonged complement activation in the central nervous system during herpes simplex encephalitis
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- 作者：Charlotta E. Erikssona ; charlotta.eriksson@gu.se" class="auth_mail" title="E-mail the corresponding author ; Marie Studahla ; b ; Tomas Bergströ ; ma
- 关键词：Complement activation ; Herpes simplex virus type 1 ; Herpes simplex encephalitis ; Central nervous system infection ; Anaphylatoxins
- 刊名：Journal of Neuroimmunology
- 出版年：2016
- 出版时间：15 June-15 July 2016
- 年：2016
- 卷：295-296
- 期：Complete
- 页码：130-138
- 全文大小：1097 K
文摘
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Intrathecal complement activation was seen during HSE.
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Increased complement activity was found in HSE patients in acute infection.
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Complement concentrations remained high in follow-up HSE patient samples.
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Anaphylatoxins C3a and C5a could contribute to neuroinflammation in HSE patients.