Quantitative muscle ultrasound as a biomarker in Charcot-Marie-Tooth neuropathy

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• 作者：N. Shahrizaila^a ; ^b ; ^{nortina@um.edu.my} ; Y. Noto^a ; N.G. Simon^c ; W. Huynh^a ; K. Shibuya^a ; J.M. Matamala^a ; T. Dharmadasa^a ; E. Devenney^a ; M.L. Kennerson^d ; G.A. Nicholson^d ; M.C. Kiernan^a
• 关键词：Muscle ultrasound ; Charcot-Marie-Tooth ; Nerve ultrasound ; Outcome biomarkers ; CMT Neuropathy Score
• 刊名：Clinical Neurophysiology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：128
• 期：1
• 页码：227-232
• 全文大小：466 K
• 卷排序：128

文摘

Charcot-Marie-Tooth (CMT) patients have increased muscle echogenicity of hand and lower leg muscles. In CMT, the volume and thickness of the hand and lower leg muscles correlate with muscle strength. CMT patients with worse muscle strength have reduced muscle thickness but increased echogenicity.