Differential expression of sex hormone receptors in abdominal aortic aneurysms

详细信息    查看全文

• 作者：Christina Villard^a ; ^b ; ^{christina.villard@ki.se} ; Per Eriksson^c ; Malin Kronqvist^a ; Mariette Lengquist^a ; Carl Jorns^d ; Johan Hartman^e ; Joy Roy^a ; ^b ; Rebecka Hultgren^a ; ^b
• 关键词：Abdominal aortic aneurysm ; Gender ; Sex hormones ; Estrogen receptor ; Androgen receptor
• 刊名：Maturitas
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：96
• 期：Complete
• 页码：39-44
• 全文大小：1452 K
• 卷排序：96

文摘

The expression of sex hormone receptors in abdominal aortic aneurysms differs from that in healthy aorta. There are greater mRNA- and protein expressions of androgen receptors in abdominal aortic aneurysms. There are lower mRNA- and protein expressions of estrogen receptor β in abdominal aortic aneurysms. Expressions of sex hormone receptors are similar in men and women with abdominal aortic aneurysm. Sex hormone activity may be associated with the development of aneurysms.