Assessment of stability of drug biomarkers in municipal wastewater as a factor influencing the estimation of drug consumption using sewage epidemiology
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- 作者：Ivan Senta ; Ivona Krizman ; Marijan Ahel ; Senka Terzic ; terzic@irb.hr" class="auth_mail
- 关键词：Illicit drugs ; Stability ; Urinary biomarkers ; Degradation ; Transformation ; Municipal wastewater
- 刊名：Science of the Total Environment
- 出版年：15 July 2014
- 年：2014
- 卷：487
- 期：Complete
- 页码：659-665
- 全文大小：358 K
文摘
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Stability of fourteen urinary drug biomarkers in municipal wastewater was evaluated.
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The most unstable compounds were cocaine, morphine glucuronide and 6-acetyl morphine.
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The degradation followed pseudo first order kinetics and was temperature dependent.
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The effect of in-sewer degradation on drug consumption estimates is relatively small.