Abnormal decision-making in generalized anxiety disorder: Aversion of risk or stimulus-reinforcement impairment?
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- 作者：Cindy Teng ; Marcela Otero ; Marilla Geraci ; R.J.R. Blair ; Daniel S. Pine ; Christian Grillon ; Karina S. Blair
- 关键词：GAD ; Decision-making ; Stimulus-reinforcement learning ; Passive avoidance ; Global assessment of functioning ; Reward ; Punishment
- 刊名：Psychiatry Research
- 出版年：2016
- 出版时间：30 March 2016
- 年：2016
- 卷：237
- 期：Complete
- 页码：351-356
- 全文大小：539 K
文摘
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We examine decision-making in 39 medication-free patients with GAD.
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29 age, IQ and gender matched healthy individuals serve as comparison individuals.
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Patients with GAD show decision-making impairment on our passive avoidance task.
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Their extent of impairment was associated with their real life functional impairment.
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Thus, a problem with reinforcement representation may contribute to GAD severity.