A ²³Na NMR study of the effect of d(+) and l(−) arabitol on NaDNA in aqueous solution

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• 作者：Marincola ; Flaminia Cesare ; Casu ; Mariano ; Saba ; Giuseppe ; Lai ; Adolfo ; del Vecchio ; Pompea ; et. al.
• 关键词：²³Na NMR ; DNA ; Arabitol
• 刊名：International Journal of Biological Macromolecules
• 出版年：2001
• 出版时间：December 10, 2001
• 年：2001
• 卷：29
• 期：4-5
• 页码：237-241
• 全文大小：129 K

文摘

The ²³Na NMR quadrupolar relaxation in NaDNA aqueous solutions has been investigated in the presence of d(+) and l(−) arabitol. Quite different results were produced by the enantiomers, i.e. the addition of d(+) arabitol produced a small increase of the ²³Na NMR relaxation rates, while in the presence of l(−) arabitol a significant decrease was observed. These findings were analysed and discussed in terms of an effective interaction of l(−) arabitol with DNA.