Erratum to “Blood oxygen saturation during atrio-ventricular dissociation with wide-QRS complex tachycardias” [International Journal of Cardiology 107/1 (2006) 134–135]

详细信息    查看全文

• 作者：Germanas Marinskis ; Gregory Y.H. Lip ; Audrius Adietis ; Paulius Jurkuvė ; nas ; Diana Kairevič ; iū ; te ; Vladimir Jež ; ov ; Kę ; stutis Bagdonas ; Pranas Š ; erpytis ; Aleks ; ras Laucev
• 关键词：Decision analysis ; Implantable cardioverter– ; defibrillator ; Primary prevention ; Quality-adjusted life years ; Reduced left ventricular ejection fraction
• 刊名：International Journal of Cardiology
• 出版年：2008
• 出版时间：11 January 2008
• 年：2008
• 卷：123
• 期：2
• 页码：217
• 全文大小：62 K

文摘

Effects of prophylactic implantable cardioverter–defibrillator (ICD) on quality-adjusted life years (QALYs) in patients with congestive heart failure are uncertain.

Methods

We developed a decision model for patients at risk of sudden death due to reduced ejection fraction and who had no history of life-threatening ventricular arrhythmias. It estimated the QALYs for ICD strategy as a primary prevention for sudden cardiac death and conventional strategy without antiarrhythmic therapies.

Results

In a 3-year time period, the QALYs for patients with conventional strategy were higher than that of ICD strategy (2.19 years vs. 2.14 years). When the mortality rate of conventional strategy exceeded 8.6 % /year and the hazard ratio of death for the ICD strategy was lower than 0.70, the ICD strategy was the superior treatment option.

Conclusions

The QALYs of patients with ICD could be lower than that of conventional strategy. Incorporating quality of life could affect decision making of ICD implantation.