Impact of ultrasound-assisted extraction on quality and photostability of the Pothomorphe umbellata extracts
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- 作者：Fernanda Steger de Oliveira Costaa ; Cé ; sar Aparí ; cio de Araú ; jo Jú ; niora ; Emmanuelle de Jesus Silvaa ; Maria Teresa Freitas Barab ; Eliana Martins Limaa ; Marize Campos Valadaresc ; Ricardo Neves Marretoa ; ricardomarreto@farmacia.ufg.br"" rel=""nofollow
- 关键词：Photostability ; Antioxidant activity ; Ultrasound energy ; 4-Nerolidylcatechol
- 刊名：Ultrasonics Sonochemistry
- 出版年：2011
- 出版时间：September 2011
- 年：2011
- 卷：18
- 期：5
- 页码：1002-1007
- 全文大小：565 K
文摘
Pothomorphe umbellata (L.) Miq. is a Brazilian shrub with therapeutic and economic applications. There are some reports on the technological development of P. umbellata preparations; however, there are no studies on the influence of non-conventional extraction procedures on the quality of P. umbellata extracts. The aim of this study was to evaluate the effects of the ultrasound-assisted extraction (UE) parameters upon the extraction yield (EY % ) of 4-nerolidylcatechol (4-NC) and the antioxidant activity of P. umbellata extracts using a factorial design and response surface methodology. Extracts obtained by UE and percolation were compared, and the photostability of 4-NC was evaluated via the exposure of UVA and visible light to the samples. The most influential variables observed for the UE were the ethanol-to-water and drug-to-solvent ratios. UE improved the extraction kinetics of 4-NC from plant material and improved the antioxidant activity of the extracts. Some of the ultrasound extracts showed an antioxidant activity that was not proportional to their 4-NC concentration, which suggests the presence of other active antioxidant compounds in these P. umbellata extracts. There was no significant difference in the photostability of 4-NC between the percolated and ultrasound extracts. Surprisingly, the isolated 4-NC material was significantly more stable when exposed to UVA-visible light compared to 4-NC in the plant extracts.