Distinct regulation of atonal in a visual organ of Drosophila: Organ-specific enhancer and lack of autoregulation in the larval eye

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• 作者：Qingxiang Zhou^a ; Linlin Yu^a ; Markus Friedrich^b ; ^c ; Francesca Pignoni^a ; ^d ; ^{PignoniF@Upstate.edu}
• 关键词：Atoh7 ; Ath5 ; RDGN ; RDN ; Neurogenesis ; Eye evolution
• 刊名：Developmental Biology
• 出版年：2017
• 出版时间：1 January 2017
• 年：2017
• 卷：421
• 期：1
• 页码：67-76
• 全文大小：1338 K
• 卷排序：421

文摘

Control of ato induction in BO is separate from compound eye or ocellar regulation. Unlike in other Ato-dependent organs, all BO control lies 5’ to transcription unit. Cis-sites for retinal determination factor Sine oculis mediate onset of ato in BO. Unlike in adult eyes and ocelli, ato does not autoregulate in BO founder neurons. atoBO is an apparently novel CRM for ato transcriptional regulation in the Bolwig’s.