Acanthamoeba keratitis due to genotype T11 in a rigid gas permeable contact lens wearer in Spain

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• 作者：Jacob Lorenzo-Morales^a ; ^b ; Rafael Morcillo-Laiz^c ; Carmen Mª ; Mart&#xed ; n-Navarro^a ; Rogelio Ló ; pez-Vé ; lez^d ; Atteneri Ló ; pez-Arencibia^a ; Francisco Arnalich-Montiel^c ; Sutherland K. Maciver^b ; Basilio Valladares^a ; ^{bvallada@ull.es} ; Enrique Mart&#xed ; nez-Carretero^a
• 关键词：Acanthamoeba ; Keratitis ; Spain ; T11
• 刊名：Contact Lens and Anterior Eye
• 出版年：2011
• 出版时间：April 2011
• 年：2011
• 卷：34
• 期：2
• 页码：83-86
• 全文大小：202 K

文摘

A case of a 59-year-old Spanish patient who presented with severe ocular pain, blurred vision, eyelid swelling and foreign body sensation in the right eye is reported. She was a regular soft contact lens wearer who initially claimed to maintain standard lens care. After exploration, conjunctival injection, dendritiform corneal ulcers and stromal edema were observed. She was initially treated for a possible viral keratitis due to herpes simplex virus using 3 % topical acyclovir and 0.1 % dexamethasone eye drops 5 times a day. The patient did not respond to this treatment and six weeks later, corneal scrapings were positive for Acanthamoeba genotype T11. She was then treated with chlorhexidine 0.02 % , propamidine 0.1 % and 1 % cycloplegic eye drops hourly which resulted in a significant improvement. After a month, ocular pain decreased and the clinical signs of keratitis ameliorated observed as a diminution of the size of the ulcer and also in the extension and opacity of the corneal infiltrates. The patient has been following this treatment for 3 months and it is possible that she will have to carry on with it for a whole year. To the best of our knowledge, this is the first case of severe keratitis due to Acanthamoeba genotype T11 in Spain.