The ability for cocaine and cocaine-associated cues to compete for attention
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- 作者：Kyle K. Pitchers<sup> ; sup><sup>pitchers@umich.edusup> ; Taylor R. Wood ; Cari J. Skrzynski ; Terry E. Robinson ; Martin Sarter
- 关键词：Addiction ; Sign-tracking ; Goal-tracking ; Cocaine ; Discriminative stimulus ; Intermittent access ; Attention
- 刊名：Behavioural Brain Research
- 出版年：2017
- 出版时间：1 March 2017
- 年：2017
- 卷：320
- 期：Complete
- 页码：302-315
- 全文大小：3480 K
- 卷排序：320
文摘
A classically conditioned auditory cue elicited cue-induced drug seeking in STs and GTs. Intermittent Access cocaine self-admin produced escalation of drug intake. Intermittent Access cocaine self-admin produced robust stimulus control over self-admin behavior. Auditory cocaine cue elicited cocaine-seeking but did not disrupt performance of a sustained attention task. Cocaine availability, contingent on the discriminative stimulus or non-contingently, severely disrupted attention task performance.