Automated cytochrome c oxidase bioassay developed for ionic liquids‿toxicity assessment
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- 作者：Susana P.F. Costa ; Bá ; rbara S.F. Martins ; Paula C.A.G. Pinto ; ppinto@ff.up.pt" class="auth_mail" title="E-mail the corresponding author ; M. Lú ; cia M.F.S. Saraiva ; lsaraiva@ff.up.pt" class="auth_mail" title="E-mail the corresponding author
- 关键词：ILs ; ionic liquids ; SIA ; sequential injection analysis ; CytCox ; cytochrome c oxidase ; FeC ; ferrocytochrome c ; emim [BF4] ; 1-ethyl-3-methylimidazolium tetrafluoroborate ; emim [Tf2N] ; 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide ; emim [Ms] ; 1-ethyl-3-methylimidazolium methanesulfonate ; emim [TfMs] ; 1-ethyl-3-methylimidazolium trifluoromethanesulfonate ; bmim [BF4] ; 1-butyl-3-methylimidazolium tetrafluoroborate ; bmim [Cl] ; 1-butyl-3-methylimidazolium chloride ; hmim [Cl] ; 1-hexyl-3-m
- 刊名：Journal of Hazardous Materials
- 出版年：2016
- 出版时间：15 May 2016
- 年：2016
- 卷：309
- 期：Complete
- 页码：165-172
- 全文大小：1223 K
文摘
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Development of the first automated cytochrome c oxidase inhibition assay based on SIA.
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The developed methodology was validated through evaluation of 15 ILs toxicity.
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The influence of different structural elements on ILs toxicity was studied.
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A rigorous control of the analytical parameters was obtained through computer control