Altered material properties are responsible for bone fragility in rats with chronic kidney injury
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- 作者：Yoshiko Iwasakia ; Junichiro J. Kazamab ; jjkaz@med.niigata-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Hideyuki Yamatoc ; Aira Matsugakid ; Takayoshi Nakanod ; Masafumi Fukagawae
- 关键词：Chronic kidney injury ; Pentosidine ; Biological apatite ; Elastic bone mechanical property
- 刊名：Bone
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：81
- 期：Complete
- 页码：247-254
- 全文大小：734 K
文摘
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The roles of uremia in the bone abnormalities were examined in uremic rats.
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In uremic animals, bone viscoelastic mechanical properties were deteriorated.
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Pentosidine-to-matrix ratio was increased.
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The degree of orientation of the c-axis in biological apatite was decreased.
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These abnormalities showed no relations to the parathyroid function.