Molecularly imprinted polymers with halogen bonding-based molecular recognition sites

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• 作者：Toshifumi Takeuchi ; Yuji Minato ; Masayoshi Takase and Hideyuki Shinmori
• 关键词：Halogen bonding ; Molecularly imprinted polymer ; Molecular recognition
• 刊名：Tetrahedron Letters
• 出版年：2005
• 出版时间：26 December 2005
• 年：2005
• 卷：46
• 期：52
• 页码：9025-9027
• 全文大小：98 K

文摘

Molecular recognition materials bearing halogen bonding-based binding sites were synthesized by a non-covalent imprinting technique using a 2,3,5,6-tetrafluoro-4-iodostyrene (TFIS) as the functional monomer. The binding sites were generated by co-polymerizing TFIS, styrene and divinylbenzene in the presence of the template molecule (4-dimethylaminopyridine—DMAP). The imprinted polymer preferentially adsorbed aminopyridine derivatives, suggesting that halogen bonding may play a role in the selective recognition of analytes by the synthesized synthetic receptor.