An age of enlightenment for cilia: The FASEB summer research conference on the “Biology of Cilia and Flagella”

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• 作者：Pamela V. Tran^a ; ^{ptran@kumc.edu" class="auth_mail" title="E-mail the corresponding author} ; Karl F. Lechtreck^b ; ^{lechtrek@uga.edu" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Arl3 ; Arl13b ; Axoneme ; Bardet&ndash ; Biedl syndrome (BBS) ; Calcium ; Ciliopathy ; Ciliary membrane ; Craniofacial defects ; Diabetes ; Dynein ; GPCR ; Hedgehog signaling ; Intraflagellar transport (IFT) ; Motility ; NPHP ; Obesity ; Phosphoinositide ; Polycystin ; Transition zone ; Tubulin
• 刊名：Developmental Biology
• 出版年：2016
• 出版时间：15 January 2016
• 年：2016
• 卷：409
• 期：2
• 页码：319-328
• 全文大小：5590 K

文摘

From July 19–24, 2015, 169 clinicians and basic scientists gathered in the vertiginous heights of Snowmass, Colorado (2502 m) for the fourth FASEB summer research conference on the ‘Biology of Cilia and Flagella’. Organizers Maureen Barr (Rutgers University), Iain Drummond (Massachusetts General Hospital/Harvard Medical School), and Jagesh Shah (Brigham and Women's Hospital/Harvard Medical School) assembled a program filled with new data and forward-thinking ideas documenting the ongoing growth of the field. Sixty oral presentations and 77 posters covered novel aspects of cilia structure, ciliogenesis, cilia motility, cilia-mediated signaling, and cilia-related disease. In this report, we summarize the meeting, highlight exciting developments and discuss open questions.