Prostate Cancer: Beta Control Your Hormones

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• 作者：Massimo Loda ; William G. Kaelin Jr.
• 刊名：Cancer Cell
• 出版年：2010
• 出版时间：13 April 2010
• 年：2010
• 卷：17
• 期：4
• 页码：311-312
• 全文大小：113 K

文摘

Differentiation status influences the prognosis for localized prostate cancer. In this issue of Cancer Cell, Mak and coworkers describe a signaling pathway involving estrogen receptor β (ERβ) that governs whether prostate carcinoma cells maintain an epithelial phenotype or undergo epithelial-mesenchymal transition, suggesting that ERβ would have prognostic or therapeutic value.