We present the characteristics as well as the surgical outcome and its determinants of a cohort of 208 consecutive patients operated on for drug-resistant posterior cortex epilepsy with a long postsurgical follow-up (mean 9.6 years). We also highlight the differences (i) between patients who necessitated an invasive preoperative evaluation and those who proceeded directly to surgery and (ii) between adults and children. Results:

a) 70% of subjects achieved seizure freedom and further 10% are in Engel class II;

b) duration of epilepsy represents a most consistent predictor of surgical outcome, with early surgery being correlated with higher chances of surgical success;

c) surgical failure might be predicted very early, namely within the first 6 postoperative months.