CF02334 is a selective inhibitor of BVDV.
Resistant viruses carry mutation N264D in the RdRp.
CF02334-resistant pestiviruses show cross-resistant to known pestivirus inhibitors.
CF02334 is inactive in an in vitro BVDV RdRp assay.
CF02334 does inhibit the activity of BVDV replication complexes.