Supplementation of infant formulas with recombinant human lactoferrin and/or galactooligosaccharides increases iron bioaccessibility as measured by ferritin formed in Caco-2 cell model

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• 作者：Esmat Aly^a ; ^b ; ^{esmat_rayan_2010@yahoo.com} ; ^{esmat.aly@um.es} ; Rubé ; n Ló ; pez-Nicolá ; s^a ; ^{rubenln@um.es} ; Aliaa Ali Darwish^b ; ^{aliaa-2006-55@hotmail.com} ; Carmen Frontela-Saseta^a ; ^{carmenfr@um.es} ; Gaspar Ros-Berruezo^a ; ^gros@um.es
• 关键词：First infant formula ; Lactoferrin ; Galactooligosaccharides ; In vitro digestion ; Caco-2 cell model ; Ferritin ; Fe bioaccessibility
• 刊名：Food Research International
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：89
• 期：part_P3
• 页码：1048-1055
• 全文大小：537 K
• 卷排序：89

文摘

This is a novel study of nutritional functionality of human lactoferrin and galactooligosaccharides in infant formula. Recombinant human lactoferrin (hLf) determines iron solubility as well as bioaccessibility in infant formula High percentage of hLf remains stable after in vitro digestion (IVD) and modulates iron bioaccessibility Released peptides after IVD of hLf increase Fe solubility and intestinal cell uptake