The effect of methacrylation on the behavior of Gum Arabic as pH-responsive matrix for colon-specific drug delivery
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文摘

Gum Arabic (GA)-based gels with different degrees of methacrylation have been prepared.

GA hydrogels show methacrylation degree- and pH-responsive properties.

Curcumin (CUR)-containing GA hydrogels were synthesized and characterized.

Delivery of CUR to simulated fluids depends on the pH and on methacrylation of GA.

GA hydrogels show promising potential for colon-specific drug delivery.

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