Cognitive impairment in progressive supranuclear palsy-Richardson’s syndrome is related to white matter damage
详细信息 查看全文
- 作者：Francesca Casoa ; Federica Agostaa ; Maria Antonietta Volonté ; b ; Pilar M. Ferraroa ; Pietro Tiraboschid ; Massimiliano Copettie ; Paola Valsasinaa ; Monica Falautanob ; Giancarlo Comib ; Andrea Falinic ; Massimo Filippia ; b ; filippi.massimo@hsr.it" class="auth_mail" title="E-mail the corresponding author
- 关键词：Progressive supranuclear palsy syndrome ; Cognition ; Diffusion tensor MRI ; White matter damage ; Cortical thickness
- 刊名：Parkinsonism & Related Disorders
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：31
- 期：Complete
- 页码：65-71
- 全文大小：957 K
文摘
- •
PSPs is characterized by focal frontal cortical thinning and distributed WM damage.
- •
WM damage is highly associated with cognitive deficits in PSPs.
- •
DT MRI metrics are the most sensitive markers of cognitive deficits in PSPs.