The aetiology of wobbly possum disease: Reproduction of the disease with purified nidovirus
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- 作者：Julia Giles ; J.C.Giles@Massey.ac.nz" class="auth_mail" title="E-mail the corresponding author ; Matthew Perrott ; Wendi Roe ; Magdalena Dunowska
- 关键词：Arterivirus ; Wobbly possum disease ; WPD ; Australian brushtail possum ; Trichosurus vulpecula ; Koch׳s postulates ; Aetiology
- 刊名：Virology
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：491
- 期：Complete
- 页码：20-26
- 全文大小：1319 K
文摘
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Experimental reproduction of wobbly possum disease (WPD).
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Three types of infectious inocula used, including the purified nidovirus isolate.
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WPD diagnosed in 11/12 infected possums based on clinical signs and histopathology.
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High levels of viral RNA in tissues of WPD-affected possums, but not in controls.
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Our data support aetiological involvement of novel possum nidovirus in WPD.