Inhaled Cannabis for Chronic Neuropathic Pain: A Meta-analysis of Individual Patient Data
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- 作者：Michael H. Andreae&lowast ; ; mhandreae@gmail.com" class="auth_mail" title="E-mail the corresponding author ; George M. Carter&dagger ; ; Naum Shaparin&lowast ; ; Kathryn Suslov&Dagger ; ; Ronald J. Ellis§ ; ; Mark A. Ware¶ ; ; Donald I. Abrams‖ ; Hannah Prasad&lowast ; &lowast ; ; Barth Wilsey&lowast ; &lowast ; ; Debbie Indyk&Dagger ; ; Matthew Johnson&dagger ; &dagger ; ; Henry S. Sacks&Dagger ;
- 关键词：Cannabis ; chronic pain ; neuropathy ; painful ; polyneuropathy ; meta-analysis ; meta-analysis of individual patient data ; Bayesian analysis ; human immunodeficiency virus
- 刊名：The Journal of Pain
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：16
- 期：12
- 页码：1221-1232
- 全文大小：805 K
文摘
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Inhaled cannabis appears to provide short-term relief from chronic neuropathic pain for 1 in 5 to 6 patients treated.
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Our novel Bayesian hierarchical model allowed the synthesis of all available patient data from 5 RCTs with disparate design and outcome reporting.
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Pragmatic long-term studies are needed to confirm the safety and effectiveness of inhaled cannabis for chronic neuropathic pain in the community.