Oral mucosal lesions in non oral habit diabetic patients and association of diabetes mellitus with oral precancerous lesions

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• 作者：Rajan Saini ; Sadeq Ali Al-Maweri ; Deepti Saini ; Noorliza Mastura Ismail ; Abdul Rashid Ismail
• 关键词：Diabetes mellitus ; Oral mucosal lesions ; Metabolic control ; Precancerous lesions
• 刊名：Diabetes Research and Clinical Practice
• 出版年：2010
• 出版时间：September 2010
• 年：2010
• 卷：89
• 期：3
• 页码：320-326
• 全文大小：203 K

文摘

Aims

This study was aimed to determine the prevalence of oral mucosal lesions (OML) in patients with diabetes mellitus (DM) and non-diabetic subjects without any oral habits and to investigate the association of DM with oral precancerous lesions.

Methods

This cross-sectional study involved 420 diabetic and 420 non-diabetic control subjects without any oral habits. Detailed oral examination was performed based on international criteria.

Results

A significantly greater proportion of subjects with DM (45 % ) had one or more OML in comparison to non-diabetics (38.3 % ). Patients with DM showed a significantly greater prevalence of geographic tongue, denture stomatitis and angular cheilitis than non-diabetics (p < 0.05). The results also showed an association between occurrence of one or more OML and metabolic control of diabetic patients (p < 0.05). For precancerous lesions, lichen planus was found in two diabetic patients while none of controls had any precancerous lesion (p > 0.05).

Conclusions

Prevalence of OML was significantly higher in diabetic patients than non-diabetics and this prevalence was associated with the metabolic control of the patients. However, no association was observed between DM and oral precancerous lesions.