d="par0005">There is a correlation between environmental particulate matter and health effects.
dd><dt class="label">•dt><dd>d="par0010">We studied in vitro simvastatin’s potential protective effect on ROFA cytotoxicity.
dd><dt class="label">•dt><dd>d="par0015">ROFA decreased cell viability, increased ROS generation, apoptosis and senescence.
dd><dt class="label">•dt><dd>d="par0020">Pretreatment with simvastatin attenuated the adverse effects observed.
dd><dt class="label">•dt><dd>d="par0025">Simvastatin may provide protection against particulate matter-induced neurotoxicity.
dd>dl>