The NLRP3 inflammasome is a potential target of ozone therapy aiming to ease chronic renal inflammation in chronic kidney disease

详细信息    查看全文

• 作者：Gang Yu^a ; Zhiming Bai^a ; ^{Drzmbai@163.com} ; Zhiyuan Chen^b ; Hui Chen^b ; Guoren Wang^a ; Gang Wang^a ; Zhenxiang Liu^a
• 关键词：CKD ; Renal inflammation ; Ozone therapy ; NLRP3 ; IL-1β
• 刊名：International Immunopharmacology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：43
• 期：Complete
• 页码：203-209
• 全文大小：1148 K
• 卷排序：43

文摘

Ozone therapy slows down the CKD progression of 5/6 nephrectomized rats. Chronic renal injury is ameliorated by ozone therapy in 5/6 nephrectomized rats. Ozone therapy reduces chronic renal inflammation by modulating NLRP3 inflammasome. Ozone therapy might be a promising reno-protecting treatment for CKD patients.