Surface characterization, in vitro and in vivo biocompatibility of Mg-0.3Sr-0.3Ca for temporary cardiovascular implant
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- 作者：M. Bornapoura ; b ; mandana.bornapour@mail.mcgill.ca" class="auth_mail" title="E-mail the corresponding author ; H. Mahjoubib ; H. Valic ; D. Shum-Timd ; M. Cerrutib ; M. Pekguleryuza
- 关键词：Biodegradation ; Biocompatibility ; Cardiovascular stent ; Substituted hydroxyapatite ; Magnesium
- 刊名：Materials Science & Engineering C
- 出版年：2016
- 出版时间：1 October 2016
- 年：2016
- 卷：67
- 期：Complete
- 页码：72-84
- 全文大小：2394 K
文摘
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The surface active elements of Sr and Ca alter the corrosion of Mg alloy in SBF
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Sr-substituted hydroxyapatite stabilizes the surface of the Mg-0.3Sr-0.3Ca alloy
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The protective Sr-HA layer is formed in-situ not only in vitro, but also in vivo
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The ions released by the alloy improve the viability of HUVECs in in vitro test
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The Mg-0.3Sr-0.3Ca stent does not cause thrombosis after 5 weeks of implantation.