Mapping ubiquitination sites of S. cerevisiae Mcm10
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- 作者：Tianji Zhanga ; 1 ; Brandy L. Fultzb ; Sapna Das-Bradoob ; Anja-Katrin Bielinskya ; bieli003@umn.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：DNA replication ; Mcm10 ; PCNA ; Ubiquitination ; 9-1-1 checkpoint clamp
- 刊名：Biochemistry and Biophysics Reports
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：8
- 期：Complete
- 页码：212-218
- 全文大小：1503 K
文摘
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S. cerevisiae Mcm10 is ubiquitinated at lysine 372.
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Alternative ubiquitination sites exist at five specific lysine residues.
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The mcm10-K372R mutation synergizes with a 9-1-1 checkpoint deficiency.