Structured review of papers reporting specific functions in patients with cancer of the head and neck: 2006 - 2013

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• 作者：S.N. Rogers^a ; ^b ; ^{snrogers.aintree@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; N. Heseltine^c ; ^{N.F.Heseltine@liverpool.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; J. Flexen^a ; ^{aflexen@tiscali.co.uk" class="auth_mail" title="E-mail the corresponding author} ; H.R. Winstanley^d ; ^{h.r.winstanley@smd14.qmul.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; H. Cole-Hawkins^e ; ^{Holly.Cole-Hawkins@bristol.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; A. Kanatas^f ; ^{a.kanatas@doctors.org.uk" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Quality of life ; Questionnaires ; Head and neck cancer ; Review
• 刊名：British Journal of Oral and Maxillofacial Surgery
• 出版年：2016
• 出版时间：July 2016
• 年：2016
• 卷：54
• 期：6
• 页码：e45-e51
• 全文大小：1199 K

文摘

Health-related quality of life (HRQoL) focuses on 4 core domains: physical and psychological function, social interaction, disease, and treatment-related symptoms, and is a key outcome in patients with cancer of the head and neck. We reviewed papers published between 2006 and 2013 that used validated questionnaires to report functional outcome in this group. A total of 572 papers were identified and 118 of them concerned function. Specific outcomes included anxiety, chewing, maxillectomy, mucositis, pain, shoulder function, and trismus. The specific functions most often identified were xerostomia, speech or voice, and swallowing or dysphagia. A considerable body of evidence has now accumulated on HRQoL and functional outomes although the precise role of HRQoL during the planning of treatment remains controversial. Over time, the emphasis of the studies included has tended to move away from the reporting of outcomes in general to more hypothesis-driven and group-specific work.