Role of Homothorax in region specific regulation of Deformed in embryonic neuroblasts
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- 作者：Raviranjan Kumara ; b ; Maheshvari Chotaliyaa ; Sruthakeerthi Vuppalaa ; Ankush Auradkara ; 1 ; Kalyani Palasamudruma ; Rohit Joshia ; rohit@cdfd.org.in" class="auth_mail" title="E-mail the corresponding author
- 关键词：Hox ; Deformed ; Neural autoregulation ; Neuroblast ; Neuron ; Glia ; Homothorax ; Homeodomain ; Neuromere ; Maxillary ; Mandibular
- 刊名：Mechanisms of Development
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：138
- 期：part_P2
- 页码：190-197
- 全文大小：1531 K
文摘
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Dfd autoregulates itself in cells of mandibular neuromere in embryonic CNS.
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Hth shows a region specific role in regulating Dfd expression in embryonic CNS.
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Hth is critical for Dfd expression in neuroblasts of maxillary neuromere.
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Hth is not important for Dfd neural autoregulation and its role is restricted to regulating levels of Dfd.
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Homeodomain-less isoform Hth is sufficient for its role in Dfd regulation in embryonic Nbs.