The mathematical model for MED-TVC desalination system considering the Boiling Point Elevation and various thermodynamic losses, has been presented.

The computational model based on the diffusion and convection transport mechanisms and concentration polarization concept has been developed for the RO system.

Hybrid MED-RO desalination system has been studied with the maximum permeate flow production.

Sensitivity analysis is presented to study the effects of the various parameters on the system performance.

Irreversibility analysis was performed and the exergy destruction and exergetic efficiency were assessed considering the chemical and physical exergies.

Multi-objective optimization based on the irreversibility concept has been presented.