Genomic characterization of Italian Clostridium botulinum group I strains
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- 作者：Francesco Giordania ; Silvia Filloa ; Anna Anselmoa ; Anna Maria Palozzia ; Antonella Fortunatoa ; Bernardina Gentilea ; Domenico Azarnia Tehrana ; 1 ; Andrea Ciammaruconia ; Ferdinando Spagnoloa ; Valentina Pittiglioa ; Fabrizio Anniballib ; Bruna Auricchiob ; Dario De Medicib ; Florigio Listaa ; romano.lista@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：BoNT ; botulinum neurotoxin (protein) ; bont ; botulinum neuro-toxin (gene) ; kb ; kilobase ; Mb ; megabase ; bp ; base pairs ; FGI ; flagellar glycosylation island ; MLST ; MultiLocus Sequence Typing ; MLVA ; Multiple Loci Variable-number-tandem-repeat Analysis ; NGS ; Next Generation Sequencing ; SNP ; single nucleotide polymorphism ; MCMC ; Markov Chain Monte Carlo
- 刊名：Infection, Genetics and Evolution
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：36
- 期：Complete
- 页码：62-71
- 全文大小：1044 K
文摘
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We sequenced 10 Clostridium botulinum group I strains isolated in Italy.
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We phylogenetically compared these genomes with 10 previously sequenced ones.
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We studied the recombination rate and fluxes among the analyzed genomes.
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The Italian strains are heterogeneous and distributed in different lineages.
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Recombination rate is high, recombination exchanges take place between all lineage.