Effects of Deltamethrin on crayfish motor axon activity and neuromuscular transmission
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- 作者：Linlin Meng ; Pierre-Francois N.R. Meyer ; Meghan L. Leary ; Yussef F. Mohammed ; Shelbi D. Ferber ; Jen-Wei Lin ; jenwelin@bu.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Crayfish ; Opener ; Ventral superficial flexor ; Action potential ; Synaptic transmission
- 刊名：Neuroscience Letters
- 出版年：2016
- 出版时间：23 March 2016
- 年：2016
- 卷：617
- 期：Complete
- 页码：32-38
- 全文大小：1522 K
文摘
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Effects of Deltamethrin (DM) on neuromuscular junction are studied in crayfish.
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DM leads to depolarization block by a ∼20 mV step depolarization in some motor axons.
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DM shifts action potential (AP) initiation site in some axons.
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The shift could explain a reduction in synaptic delay observed in some synapses.
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The depolarization block occurs before AP duration or frequency is changed.