Evaluation of the level of thiol-disulphide homeostasis in patients with mild and severe preeclampsia

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• 作者：Hilal Uslu Yuvaci^a ; ^{hilaly@sakarya.edu.tr} ; Nermin Akdemir^a ; Mehmet Suhha Bostanci^a ; Hayrullah Yazar^b ; Serhan Cevrioglu^a ; Selç ; uk Ozden^a ; Orhan Unal^a ; Merve Keskin Paker^a ; Salim Neselioglu^c ; Ozcan Erel^c
• 刊名：Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health
• 出版年：2016
• 出版时间：October 2016
• 年：2016
• 卷：6
• 期：4
• 页码：394-399
• 全文大小：606 K
• 卷排序：6

文摘

We assessed thiol-disulphide balance with a new colorimetric method recently developed by Erel & Neşelioğlu. Native thiol (SH), total thiol (SS + SH) and disulphide (SS) levels were found to be significantly lower in severe pre-eclamptics when compared to mild pre-eclamptics and the control group (p < 0.01). Native thiol (SH), total thiol (SS + SH) and disulphide (SS) levels may have been found to be significantly low as there are low serum albumin and total protein in pre-eclamptic patients, especially in severe pre-eclampsia cases.