A species-specific activation of Toll-like receptor signaling in bovine and sheep bronchial epithelial cells triggered by Mycobacterial infections
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- 作者：Yan Maa ; b ; Fei Hanc ; Jinping Lianga ; d ; Jiali Yanga ; Juan Shia ; Jing Xueb ; Li Yange ; Yong Lib ; Meihui Luoa ; Yujiong Wangb ; Jun Weia ; f ; weijun@nxmu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Xiaoming Liua ; b ; f ; liuxiaoming@nxmu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; lxm1966@nxu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Species-specific recognition ; Toll-like receptor signaling ; Mycobacterium infection ; Sheep ; Bovine ; Airway epithelial cells
- 刊名：Molecular Immunology
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：71
- 期：Complete
- 页码：23-33
- 全文大小：4471 K
文摘
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A differentiated bovine bronchial epithelial air–liquid interface model was established.
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A species-specific TLR-mediated PAMP recognition in bovine and sheep airway epithelial cells was determined.
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Mycobacteria triggered a species-specific TLR signaling in bovine and sheep airway epithelial cells.
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Mycobacteria infections induced a species-specific inflammatory response in bovine and sheep airway epithelial cells.